Septefril-Darnitsa of the tab. of 0.2 mg No. 20

Pharmacological properties

Dekametoksin ― active pharmaceutical ingredient of medicine ― is quarternary ammonium connection from group of surfactants of cationic type. communication of decamethoxynum with phosphatic groups of lipids of a microbic plasmolemma breaks its permeability and leads to destruction of a bacterial cell.

decamethoxynum. The following microorganisms are sensitive to drug:

• staphylococcus, including the strains of golden staphylococcus resistant to penicillin;
• streptococci;
• a korinebakteriya (including causative agent of diphtheria);
• Stomatococcus spp.;
• Enterobacteriaceae;
• Pseudomonas;
• spore-forming bacteria;
• elementary;
• yeast-like mushrooms (especially Candida albicans);
• dermatophytes;
• viruses.

Effects inherent in decamethoxynum:

• bactericidal;
• fungicidal;
• sporotsidny;
• suppression of activity of Corynebacterium diphtheriae exotoxin;
• increase in sensitivity of microorganisms to influence of antibiotics.

On specific and nonspecific reactivity of the immune system of an organism decamethoxynum has no impact.

Indication

∎ diseases of an oral cavity, a throat, a throat (for topical administration as a part of complex therapy):

• tonsillitis;

• pharyngitis;

• laryngitis;

• ulitis;

• stomatitis;

• periodontal disease;

• candidosis damages of a mucous membrane of an oral cavity;

• tonsillitis (initial stage).

∎ Carriage of pathogenic Staphylococcus spp., C. diphtheriae, Candida spp. (for the purpose of sanitation of an oral cavity, a throat, a nasopharynx).

∎ After the undergone surgeries in an oral cavity, a drink, a throat (for prevention of infectious complications).

Use

After rinsing of an oral cavity use a bukkalny method of administration of medicine (the tablet has to be in an oral cavity before full resorption). the adult ― on 1 tablet from 4 to 6 times a day after a meal. to avoid meal and drinks during 1 h after use of medicine. treatment duration ― ≤1 week

Contraindication

Hypersensitivity to decamethoxynum or other components of medicine.

Side effects

Allergic reactions (including skin rash); itch of integuments.

.

Special instructions

for the purpose of increase in content of decamethoxynum in saliva needs to swallow as seldom as possible of it in the course of medicine resorption.

does not recommend the combined use of medicine with different types of rinsing of a stomatopharynx.

medicine Use more than 1 week can contribute to the development of a microbic imbalance of a throat.

For patients with diabetes needs to take existence in composition of medicine of sugar into account.

Use during pregnancy and feeding by a breast. Clinical trials of safety of use of medicine for pregnant women and during feeding by a breast did not carry out. During pregnancy the intake of decamethoxynum is not recommended. In case of need use of decamethoxynum needs to be interrupted feeding with a breast.

Children. There are no clinical data on use of medicine (efficiency and safety) in the specified age group.

Influence on speed of response at control of vehicles or other mechanisms. No.

Interaction

Antibacterial effect of decamethoxynum amplifies at its combined application with the antibiotics and antimicrobial means having system effect.

Overdose

Data are absent.

Storage conditions

At a temperature of ≤25 °C in original packing.