Magnikor of the tab. of p/o No. 30

Magnikor is recommended for appointment as the patient with chronic and acute coronary heart disease (in unstable stenocardia, an acute myocardial infarction). Also, Magnikor is appointed for the purpose of prevention of repeated formation of blood clots.

Drug is also appointed for prevention of pathologies of a cardiovascular system (at a sharp coronary syndrome).

Indication to use Magnikor can be a hypercholesterolemia, obesity, diabetes. Also he is appointed the patient aged up to 55 years which transferred a myocardial infarction in the past.

Structure

Active ingredients: Magnikor contains in one tablet 75 mg acetilsalicylic to - you, 15.2 mg of magnesium of hydroxide (Magnikor Forte contains 150 mg of acetylsalicylic acid, 30.39 mg of magnesium of hydroxide).

Excipients: corn starch, microcrystalline cellulose, potato starch, magnesium stearate, mix for a film covering.

Contraindication

is strictly forbidden to be accepted Magnikor in the following cases:

• individual intolerance of the components (such as salicylic acid and its derivatives) which are a part of medicine;
• stomach ulcer in an aggravation phase;
• increased risk of developing of bleedings (deficiency of vitamin K, an anemia, thrombocytopenia);
• a renal and liver failure in a severe form;
• heart failure
• asthma or a Quincke's edema against the background of reception of NPVP or salicylates in the anamnesis
• last trimester of pregnancy;
• to patients of children's age.

Route of administration

Before use, at treatment and prevention of serious diseases, is recommended to consult with the doctor. Time of treatment and a dosage need to be selected individually, according to your disease.

recommends to take a pill Magnikor entirely, washing down in case of need. If desired it is possible to pound a tablet, to chew or pull down.

In acute or chronic form of coronary heart disease recommends an initial dosage in 150 mg a day. A maintenance dose of 75 mg a day.

In stenocardia and an acute myocardial infarction a daily dose ravnyaetsya150 mg - 450 mg. Magnikor is recommended to begin use at the first symptoms appeared.

For prevention of a thrombogenesis: daily dose of 150 mg. A support dose - 75 mg a day.

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Feature of use

Pregnant

Before use Magnikor needs to consult with the doctor. If expected positive effect from therapy Magnikor for mother considerably exceeds risk of threat to a fruit, then use of medicament is possible during the period from 1 to 6 month of pregnancy.

only in the minimum doses - up to 100 mg a day under strict observation of the doctor.

not to use

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Driver

does not influence.

Overdose Magnikor is possible

at a daily dose of 150 mg on 1 kg of body weight.

At prolonged use Magnikor in high doses (more than 150 mg on 1 kg a day) moderately severe perhaps chronic poisoning. Symptoms of similar poisoning are: dizziness, deafness, sonitus, vasodilatation, perspiration, nausea, vomiting, confusion of consciousness, headache.

Serious acute poisoning Magnikor can cause such symptoms: spontaneous concern, hyperventilation of lungs, alkaloidal alkalosis, high temperature, ketosis and metabolic acidosis. Among consequences of a serious poisoning Magnikor it should be noted oppression of the central nervous system which can lead to a coma, cardiovascular collapse and an apnoea.

Overdose of salicylic acid and its derivatives usually causes an acute liver failure (at a dosage more than 300 mg/kg). A lethal dose for the person are more than 500 mg/kg.

At overdose needs to wash out immediately a stomach and to allow the victim to accept activated carbon. It is also very important to restore water and electrolytic balance for avoidance of developing of acidosis, dehydration, a hyper pyrexia and a hyperpotassemia.

Among effective methods of removal of salicylate from the circulating blood should mention a hemodialysis, hemoperfusion and an alkaline diuresis.

Side effects

Hypersensitivity reaction with the corresponding laboratory and clinical manifestations, including asthmatic the state, skin reactions of easy or average degree and also from a respiratory path, digestive tract and a cardiovascular system, including such symptoms as rash, urticaria, hypostasis, an itching, rhinitis, congestion of a nose, cardiorespiratory insufficiency and is very rare - heavy reactions, including an acute anaphylaxis.

Interaction

Magnikor at a concomitant use strengthens effect of anticoagulants (such as warfarin, heparin, klopidogrel, fenprokumon) and hypoglycemic medicines. Drug supressirut diuretic effect of furosemide, action of APF, Spironolactonum oppresses.

Magnikor along with NPVS. Antiacid medicaments worsen absorption of this medicine. Use along with probenetsidy reduces effect of both drugs.

Significant mutual influence of acetylsalicylic acid and magnesium at use of medicament it is noted p. Perhaps, it is caused by small amount of magnesium, being a part.

to Store

at a temperature not above 25 °C in the place, dry and inaccessible for children.

Expiration date - 2 years.