Biolektra Magnezium Fortissimum of the tab. thorn. No. 10

Pharmacological properties

Thanks to the central role in a metabolism magnesium is an important element for an organism. magnesium is necessary for ensuring many power processes in an organism, he participates in exchange of proteins, fats, carbohydrates, nucleic acids and in the course of neuromuscular excitement.

Numerous functions of generation or power consumption (as, for example, chemical changes, transport macro - and microelements, reduction of muscles) depend on magnesium and at disturbances of providing an organism with magnesium can be carried out in insufficient degree or be broken completely.

Magnesium activates glucose splitting enzymes, enzymes of cellular oxidation, protein synthesis enzymes, it also plays an important role in processes of reduction of a myocardium; is the stabilizer of fibrinogen and thrombocytes. It is known that the deficiency of magnesium is one of pathogenetic mechanisms in development of AG, angiospasm, neoplastic diseases and an urolithiasis. In stressful situations the increased amount of the free ionized magnesium in this connection the additional amount of magnesium promotes increase in resistance to a stress is removed. Magnesium plays the leading role in processes of neuromuscular excitement, acting as the antagonist of calcium ions.

Total amount of magnesium in an organism of the adult makes about 20-30 g. From this number about 50% is in bones, 45% — in cells and only 5% of total can be revealed in blood plasma.

ranging from 10 up to 60 mmol/l, the normal value of concentration of magnesium is in blood plasma ranging from 0.7 up to 1.1 mmol/l. In blood plasma approximately ⅔ ions of magnesium are in the dissolved look and near ¹ / ₃ — contacts proteins.

At use depending on the initial content of magnesium in an organism. At deficiency of magnesium in an organism it is soaked up more, and at saturation by magnesium — it is less. The resorption accelerates or slows down according to requirements of an organism that is characteristic of physiologically active agents. At equilibrium balance of magnesium and the kept function of kidneys, despite high doses of magnesium, there is no increased accumulation of the magnesium exceeding limit of norm.

After absorption in intestines discharge of magnesium is carried out mainly by kidneys. Undigested magnesium is removed together with a stake.

Indication

for treatment and prevention of deficiency of magnesium in an organism when it is the reason of disturbances from muscle performance (neuromuscular disturbances, spasms), at chronic physical and intellectual fatigue, irritability, myalgias, at intensive physical and intellectual activities, during pregnancy.

At a hypomagnesiemia which arose owing to long smoking and an alcohol abuse, prolonged use of laxative, contraceptive means, some diuretics or an osmotic diuresis at patients with diabetes with a constant hyperglycemia.

Use

to Adults and children is aged more senior than 15 years appoint on 1 tablet of sparkling 1 times a day.

Tablet needs to be dissolved in a glass of water, to drink the received solution.

Duration of treatment depends on the reasons which are the cornerstone of deficiency of magnesium in an organism and is defined by the doctor individually.

Contraindication

Hypersensitivity to any component of drug.

Renal failure; disturbances of conductivity in heart (AV blockade of high degree) which can lead to bradycardia. Gipermagniyemiya, a hyperpotassemia, a heavy myasthenia, eksikoz, persistent infections of urinary tract, calcium-magnesium-phosphate - ammonium diathesis.

At higher doses the soft chair which is not dangerous and disappears after a dose decline is possible

. at long administration of medicament in high doses the feeling of fatigue can develop. in this case the doctor has to make the decision on expediency of further intake of magnesium.

Special instructions

1 sparkling tablet contains 4.65 mmol (107 mg) of sodium. need to consider it the patients keeping to a diet with the low content of sodium (with the low content of table salt).

1 sparkling tablet will gain 2.51 mmol (98 mg) of potassium. Patients need to consider it with bounded function of kidneys and also to the patients keeping to a diet with the low content of potassium.

Use during pregnancy and feeding by a breast. During pregnancy there is no risk at medicament use. Intake of medicine during feeding by a breast is recommended after consultation with the doctor and on his appointment.

Ability to influence speed of response at control of vehicles or work with other mechanisms. Does not influence.

Children. Drug is not recommended to be used at children aged up to 15 years.

Interaction

Magnesium which is a part of medicine can break digestion of iron, sodium fluoride, tetracycline. in such cases between administrations of medicament of a biolektr magnezium fortissimum and iron preparations, sodium fluoride, tetracycline it is necessary to observe an interval of 3-4 h at a concomitant use of the medicaments containing aluminum (for example antiacid means), absorption of aluminum can be increased.

Drugs of magnesium strengthen effect of antiarrhytmic and antihypertensive medicines and also the medicaments oppressing central nervous system; the concomitant use with medicaments of amphetamine, ephedrine, quinidine, quinine is not recommended.

Overdose

At intake of salts of magnesium inside the gipermagniyemiya arises only in a renal failure. intake of salts of magnesium is contraindicated to such patients.

intoxication Symptoms. High concentrations of magnesium cause relaxation of skeletal muscles (concentration of magnesium in blood plasma of 5.5 mmol/l). Higher concentrations of ions of magnesium (10–20 mmol/l) extend the conductivity period in heart, and higher concentrations lead to cardiac arrest in a diastole.

Treatment of intoxication. In/in administration of calcium instantly leads to suppression of the described symptoms as there is an antagonism between these ions.

Storage conditions

In original packing at a temperature not above 25 °C.

Exclusive distributor: CIAO Naturfarm, Lesnaya St., 30a, Kiev, Pushcha-Vodytsia, 04075; phone number: (044) 401-81-03.

Supplier: Alpen Pharm AG (Switzerland).