Atera And tab. 80mg/5mg No. 28

Atera And – a blocker of receptors of angiotensin II, a combination, for treatment of essential hypertensia at adults.

Additional therapy. And to appoint Atera medicine to adult patients at whom the ABP is not controlled adequately amlodipiny or telmisartany.

Replacement therapy. The adult patients accepting telmisartan and amlodipin in separate tablets can take the pill Atera And, the containing same doses of components.

Structure

• active ingredients: telmisartan, amlodipin;
• 1 tablet contains 80 mg of a telmisartan and 5 mg of an amlodipin (in the form of the besilat of an amlodipin);
• other components: sodium hydroxide, Megluminum, K25 povidone, ferrous oxide yellow (E 172) – only for tablets on 40 mg / 10 mg and 80 mg / 10 mg, ferrous oxide red (E 172) – only for tablets on 40 mg / 5 mg and 80 mg / 5 mg, a mannitol (E 421), cellulose microcrystalline, krospovidon, magnesium stearate, starch prezhelatinizirovanny, starch corn, silicon dioxide colloidal anhydrous.

Contraindication

• Hypersensitivity to active ingredients, to derivatives of dihydropyridine or any excipient of medicine.
• Period of pregnancy or planning of pregnancy.
• feeding Period breast.
• Obstructive biliary disturbances and heavy liver failure.
• Shock (including cardiogenic shock).
• Obstruction of output department of a left ventricle (for example stenosis of an aorta of high degree).
• Hemodynamically unstable heart failure after an acute myocardial infarction.
• Simultaneous use of a telmisartana/amlodipin with the medicaments containing aliskiren at patients with diabetes or renal failures (SKF of 60 ml/min. / 1.73 sq.m).
• Children's age up to 18 years.

Side reactions

Infection and an invasion – infrequently – upper respiratory tract infections, including pharyngitis and sinusitis, infections of urinary tract, including cystitis. Seldom – cystitis sepsis, including a lethal consequence.

from blood and lymphatic system – infrequently – anemia, it is rare – thrombocytopenia, an eosinophilia, is very rare – a leykotsitopeniya, thrombocytopenia.

from the immune system – it is rare – hypersensitivity, anaphylactic reaction, is very rare – hypersensitivity.

Disturbance of metabolism and digestion – infrequently – a hyperpotassemia, it is rare – a hypoglycemia (at patients with diabetes), is very rare – a hyperglycemia.

Mental disturbances – infrequently – change of mood, is rare – a depression, uneasiness, sleepless confusion of consciousness.

from nervous system – it is frequent – dizziness, infrequently – drowsiness, migraine, a headache, paresthesia, is rare – a syncope, peripheral neuropathy, a hypesthesia, a dysgeusia, a tremor, is very rare – an extrapyramidal syndrome.

from organs of sight – infrequently a disorder of vision.

Route of administration

Drug Atera And can be accepted irrespective of food. It is recommended to wash down tablets with a small amount of liquid.

Recommended Ater's dose And makes 1 tablet a day.

Maximum recommended dose – 1 tablet Atera And 80 mg / 5 mg/days. The medicament Atera And is intended for long-term treatment.

does not recommend use of an amlodipin with grapefruit or juice of grapefruit as the bioavailability can increase at some patients that will lead to increase in antihypertensive effect.

Tablet Atera And 80 mg / 10 mg patients at whom the ABP is not controlled by means of the tablets Atera And 40 mg / 10 mg or the tablets Atera And 80 mg / 5 by mg can accept

.

Tablet Atera And 80 mg / 5 mg can be accepted at patients at whom arterial blood pressure adequately is not controlled by means of the tablets Atera And 40 mg / 5 by mg.

Tablet Atera And 40 mg / 10 mg patients at whom the ABP is not controlled amlodipiny 10 mg can accept.

Tablet Atera And 40 mg / 5 mg patients at whom the ABP is not controlled amlodipiny 5 mg can accept.

Replacement therapy

Patients accepting telmisartan and amlodipin separate tablets, instead can take the medicament Atera And, containing the corresponding doses of the specified components in one tablet, 1 time a day daily, for example for convenience or observance of the mode of treatment.

Feature of use

Use during pregnancy or feeding by a breast

Medicine is contraindicated to pregnant women or women who are going to become pregnant. If at use of Atera medicine And pregnancy is confirmed, its use needs to be stopped and replaced immediately with other medicine allowed for use to pregnant women.

information on use of a telmisartan during feeding by a breast, use of the medicament Atera And during this period is contraindicated, it is necessary to pass to alternative therapy with better the established safety profile.

not to apply

in pediatric practice. Safety and efficiency of use of medicament are not established to children up to 18 years. Data are absent.

Ability to influence speed of response at control of motor transport or other mechanisms

This medicine has moderate impact on speed of response during the driving or work with other mechanisms. Patients should inform that during treatment such side reactions as to a syncope, drowsiness, dizziness or vertigo are possible. Therefore it is recommended to be careful during the driving or work with other mechanisms. If patients have such side reactions, they should avoid potentially dangerous works, such as driving or work with other mechanisms.

Overdose

Symptoms. The expected signs and symptoms of overdose correspond to the enhanced pharmacological effects. The most significant manifestations of overdose telmisartany consider arterial hypotension and tachycardia; also reported about bradycardia, dizziness, increase in level of creatinine in blood serum and OPN.

to excessive expansion of peripheral vessels and, perhaps, to reflex tachycardia. It was reported about expressed and, perhaps, the extended system hypotension, including shock with a lethal outcome.

Treatment. It is necessary to watch a condition of the patient carefully, treatment has to be symptomatic and supporting. Therapeutic actions depend on the use of medicament and weight of symptoms which took place later. Proposed measures include stimulation of vomiting and/or washing of a stomach. Activated carbon can be useful at overdose both telmisartany, and amlodipiny.

to Store

in original packing for protection against light.

to Store

out of children's reach.